You know, there are some parts of the cosmos that are best left undisturbed. While the universe is abundant with wonders, it may hold its own fair share of horrors. You know how far humans will go to achieve their own self-interests, and the universe will retaliate in kind by fucking us up in the ass tenfold.
I think you're right, we have no idea of knowing what sort of Pandora's Box we're opening up by expanding on our explorations, and there's no way to know if it is a box we're able to close. It seems like the natural order of things... we'll keep pushing and expanding until something pushes back. I hope to be long gone before the retaliation.
Thanks for your kind comment and question! In the case of Azathoth, it started out with a lot of random scribbling that filled the entire surface of the paper. Then, much like one might see things in cloud in the sky, I start to recognize forms in the scribbles. Then I refine those shapes to make them look more realistic. I am just as surprised with the outcome as the viewers!